Publications

 

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A.            Edited books / proceedings:

1.         Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 6087 “Biophotonics and Immune Responses”, San Jose, California, January 2006.

2.         Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 6438 “Biophotonics and Immune Responses II”, San Jose, California, January 2007.

3.         Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 6857 “Biophotonics and Immune Responses III”, San Jose, California, January 2008.

 B.            Refereed Journal Papers:

1                    Wei R. Chen and Rudolph C. Hwa, "Geometrical scaling, branching and Koba-Nielson-Olesen scaling", Physical Review D: Particles and fields, 36, 760-764, 1987.

2                    Wei R. Chen, Rudolph C. Hwa and Xing-Nian Wang,  "Particle productivity in pp and pA collisions", Physical Review D: Particles and fields, 38, 3394-3396, 1988.

3                    Wei R. Chen and Rudolph C. Hwa,  "Geometrical Branching model: Phenomenology with jets", Physical Review D: Particles and fields, 39, 179-186, 1989.

4                    Wei R. Chen, Rudolph C. Hwa and Xin-Nian Wang, "Cluster cascading in the geometrical branching model", Physical Review D: Particles and fields, 43, 2425-2428, 1991.

5                    Moustafa Bahran, Wei R. Chen and George R. Kalbfleisch,  "Fermi theory of nuclear b decay and heavy neutrino searches", Physical Review D: Particles and fields, 47, (Rapid Communications) R759-R763, 1993.

6                    Wei R. Chen, Robert L. Adams, Sean Heaton, D. Thomas Dickey, Kenneth E. Bartels and Robert E. Nordquist, "Chromophore-enhanced laser-tumor tissue photothermal interaction using 808 nm diode laser", Cancer Letters, 88, 15-19, 1995.

7                    Wei R. Chen, Robert L. Adams, Kenneth E. Bartels and Robert E. Nordquist, “Chromophore-enhanced in vivo tumor cell destruction using an 808-nm diode laser”, Cancer Letters, 94, 125-131, 1995.

8                    Wei R. Chen, Arne Troelstra, and Xifan Liu, “Acceleration of a pendulum with arbitrary releasing positions”, NCSSSMST Journal, 2, 17-22, 1995.

9                    Wei R. Chen, Robert L. Adams, Aaron K. Higgins, Kenneth E. Bartels and Robert E. Nordquist, “Photothermal effects on murine mammary tumors using indocyanine green and an 808-nm diode laser: An in vivo efficacy study”, Cancer Letters, 98, 169-173, 1996.

10                Wei R. Chen, Robert L. Adams, Raoul Carubelli and Robert E. Nordquist, “Laser-photosensitizer assisted immunotherapy: A novel modality in cancer treatment”, Cancer Letters, 115, 25-30, 1997.

11                Li-hong Wang, Robert E. Nordquist and Wei R. Chen, “Optimal beam size for light delivery to absorption-enhanced tumors buried in biological tissues and effect of multiple beam delivery: a Monte Carlo study”, Applied Optics Vol. 36, 8286-8291, 1997.

12                Wei R. Chen and Arne A. Troelstra, “The kinetic energy of a rotating figure skater”, NCSSSMST Journal, Vol. 3(2), 3-5, 1998.

13                Joy Lin, Arne A. Troelstra and Wei R. Chen,  “Quantization of a two-body system with a 1/r4 attractive force: A hypothetical quantum atomic structure”, NCSSSMST Journal, Vol. 4(1), 9-12, 1998.

14                Wei R. Chen, Wei-Guo Zhu, Joseph R. Dynlacht, Hong Liu and Robert E. Nordquist,  “Long-term tumor resistance induced by laser photo-immunotherapy”, International Journal of Cancer, 81, 808-812, 1999.

15                Fang Xu, Hong Liu, Xizeng Wu, Hangyi Jiang, Robert E. Nordquist and Wei R. Chen, “Measurement of x-ray attenuation coefficients of aqueous solutions of indocyanine green and glycated chitosan”, Medical Physics, 26, 1371-1374, 1999.

16                Wei R. Chen, Hong Liu, John A. Nordquist and Robert E. Nordquist,  “Tumor cell damage and leukocyte infiltration after laser immunotherapy treatment”, Lasers in Medical Science, 15, 43-48, 2000.

17                Hong Liu, Hangyi Jiang, Laurie L. Fajardo, Andrew Karellas, and Wei R. Chen, “Lens distortion in optically coupled digital x-ray imaging”, Medical Physics, 27, 906-912, 2000.

18                Hangyi Jiang, Hong Liu, Ge Wang, Wei Chen and Laurie L. Fajardo, “A localization algorithm and error analysis for stereo x-ray image guidance”, Medical Physics, 27, 885-893, 2000.

19                Wei R. Chen, Anil K. Singhal, Hong Liu, and Robert E. Nordquist, “Laser immunotherapy induced antitumor immunity and its adoptive transfer”, (Advances in Brief) Cancer Research, 61, 459-461, 2001.

20                Hong Liu, Hangyi Jiang, Laurie L. Fajardo, Andrew Karellas, and Wei R. Chen, “Characteristics of lens distortion and methods to correct geometrical distortion caused by lenses in optically coupled digital x-ray imaging: A response to Dr. E. H. B. M. Gronenschild's comment”, Medical Physics, Vol. 28(6), 1139-1140, 2001.

21                Wei R. Chen, Hong Liu and Robert E. Nordquist, “Dynamically observing intratumor injection of laser-absorbing dye and immunoadjuvant using digital x-ray imaging technique”, Optical Engineering, Vol. 40 (7), 1249-1254, 2001.

22                Hangyi Jiang, Hong Liu, and Wei R. Chen, “Determination of the monoplane 3D system geometry in X-ray imaging guidance”, Journal of X-Ray Science and Technology, 9, 19-28, 2001.

23                Hangyi Jiang, Wei R. Chen, Ge Wang, and Hong Liu, “Localization error analysis for stereo x-ray image guidance with probability method”, Medical Engineering and Physics, Vol. 23, 573-581, 2001.

24                Hangyi Jiang, Wei R. Chen, and Hong Liu, “Position-dependent image characteristics of a CCD-based full-field digital mammography system”, Journal of X-Ray Science and Technology, 9, 101-111, 2001.

25                Fabrice Ouandji, Eric Potter, Wei R. Chen, Yuhua Li, David Tang, and Hong Liu, “Characterization of a CCD-based digital x-ray imaging system for small animal studies: Properties of spatial resolution”, Applied Optics, Vol. 41, No.13, 2420-2427, 2002.

26                Yuhua Li, Wei R. Chen, Yimou Zhang, Wei Qian, and Hong Liu, “Comparison of analog and digital Fourier Transforms in medical image analysis”, Journal of Biomedical Optics, Vol. 7, No. 2 255-261, 2002.

27                Wei R. Chen, Jerry W. Ritchey, Kenneth E. Bartels, Hong Liu, and Robert E. Nordquist, “Effect of different components of laser immunotherapy in treatment of metastatic tumors in rats”, Cancer Research, 62 4295-4299, 2002.

28                Vinson G. Liu, Thomas M. Cowan, Sang-Won Jeong, Steven L. Jacques, Evan C. Lemley and Wei R. Chen, “Selective photothermal interaction using an 805-nm diode laser and indocyanine green in gel phantom and chicken breast tissue”, Lasers in Medical Science, Vol. 17 No. 4, 272-279, 2002.

29                Wei R. Chen, Hong Liu, Raoul Carubelli and Robert E. Nordquist, “Synergistic Effect of Photothermal and Photoimmunological Reactions in Treatment of Metastatic Tumors”, Journal of X-Ray Science and Technology, 10, 225-235, 2002.

30                Michael D. Lucroy, Wei R. Chen, Tisha D. Ridgway, Russell G. Higbee, and Kenneth E. Bartels, “Selective laser-induced hyperthermia for the treatment of spontaneous tumors in dogs”, Journal of X-Ray Science and Technology, 10, 237-243, 2002.

31                Hangyi Jiang, Wei R. Chen, and Hong Liu, “Techniques to improve the accuracy and to reduce the variance in noise power spectrum measurement”, IEEE Transactions on Biomedical Engineering, 49, 1270-1278, 2002.

32                D. Richard Ishmael, Wei R. Chen, John Nordquist, Hong Liu, and Robert E. Nordquist, “Synergistic Effect of Sequential Administration of Mitoguazone (MGBG) and Gemcitabine in Treating Tissue Cultured Human Breast Cancer Cells and Mammary Rat Tumors”, Cancer Investigation, 21, 217-226, 2003.

33                D. Richard Ishmael, Wei R. Chen, Steven A. Hamilton, Hong Liu, and Robert E. Nordquist, “A Phase I Human Trial of Mitoguazone and Gemcitabine Sequential Bi-Weekly Treatment of Cancer Patients”, Cancer Investigation, 21, 542-549, 2003.

34                Wei R. Chen, Raoul Carubelli, Hong Liu, and Robert E. Nordquist, “Laser Immunotherapy: A Novel Treatment Modality for Metastatic Tumors”, Molecular Biotechnology, 25, 37-43, 2003.

35                Wei R. Chen, Raoul Carubelli, Hong Liu, and Robert E. Nordquist, “Detection of Anti-Tumor Immunity Induced by Laser Immunotherapy”, Molecular Biotechnology, 25, 45-51, 2003.

36                Wei R. Chen, Sang Won Jeong, Michael D. Lucroy, Roman F. Wolf, Eric W. Howard, Hong Liu, and Robert E. Nordquist, “Induced anti-tumor immunity against DMBA-4 metastatic mammary tumors in rats using a novel approach”, International Journal of Cancer, 107 (6), 1053-1057, 2003.

37                Christopher A. Bailey, Thomas M. Cowan, Vinson G. Liu, Evan C. Lemley, and Wei R. Chen, “Optimization of Selective Hyperthermia”, Journal of Biomedical Optics, 9 (3), 648-654, 2004.

38                Chang Ye, Qingming Luo, Wei R. Chen, Wenxi Liang, Weihua Luo, and Aijun Zhong, “Limitation in Detecting Internal Blood Vessels Using Digital X-ray Imaging Technique”, Journal of X-Ray Science and Technology, 12, 59-71, 2004.

39                Hemanth Athiraman, Roman F. Wolf, Kenneth E. Bartels, Suman Shivakoti, Hong Liu, and Wei R. Chen, “Selective Photothermal Tissue Interaction Using 805-nm Laser and Indocyanine Green in Tissue welding”, Journal of X-Ray Science and Technology, 12, 117-126, 2004.

40                Wei R. Chen, Mladen Korbelik, Kenneth E. Bartels, Hong Liu, Jinghai Sun, and Robert E. Nordquist, “Enhancement of laser cancer treatment by a chitosan-derived immunoadjuvant”, Photochemistry and Photobiology, 81, 190-195, 2005.

41                David Tang, Yuhua Li, Jessica Wong, Sunny Po, Eugene Patterson, Wei R. Chen, Warren Jackman, and Hong Liu, “Characteristics of a CCD-based Optical Mapping System for the Study of Cardiac Arrhythmias”, Journal of Biomedical Optics, 10, 024009-1-024009-7, 2005.

42                Qirong Zhang, Yuhua Li, Ben Steele, Xizeng Wu, Wei R. Chen, John Rong, and Hong Liu, “Comparison of a CMOS-based and a CCD-based digital x-ray imaging system: Observer studies”, Journal of Electronic Imaging, 14(2), 023002-1-023002-6, 2005.

43                Xingwei Wang, Bin Zheng, Marc Wood, Shibo Li, Wei R. Chen, and Hong Liu, “Development and evaluation of automated systems for detection and classification of banded chromosomes: current status and future perspectives”, Journal of Physics D: Applied Physics, 38, 2536–2542, 2005.

44                D. Richard Ishmael, Hong Liu, John A. Nordquist, Robert E. Nordquist, and Wei R. Chen, “Phase I Trial of Concurrent Administration of Topotecan and Docetaxel for Cancer Treatment”, Journal of Applied Research, 5, 53-60, 2005.

45                Yueqing Gu, Wei R. Chen, Mengna Xia, Sang Won Jeong and Hanli Liu, “Effects of Photothermal Therapy on Breast Tumor Vascular Contents: Noninvasive Monitoring by Near-Infrared Spectroscopy”, Photochemistry and Photobiology, 81, 1002-1009, 2005.

46                Wei R. Chen, Zheng Huang, Mladen Korbelik, Robert E. Nordquist, and Hong Liu, “Photoimmunotherapy for Cancer Treatment”, Journal of Environmental Pathology, Toxicology and Oncology, 25, 281-291, 2006.

47                Qirong Zhang, John Rong, Xizeng Wu, Yuhua Li, Wei R. Chen, and Hong Liu, “,Impacts of Filtration on Contrast-Detail Detectability of an X-ray Imaging System”, International Journal of Biomedical Imaging, Vol 2006, 95754, 1-8, 2006.

48                Zheng Huang, Qian Yong Gang and Wei R. Chen “Photodynamic Therapy and Anti-tumor Immune Responses”, Chinese Journal of Laser Medicine and Surgery, 15 (2), 121-124, 2006 (in Chinese).

49                Yunxia Wu, Da Xing, and Wei R. Chen, “Dynamic Monitoring of Photofrin-PDT Induced Apoptosis Using FRET Technique”, Cell Cycle, 5:7, 720-734, 2006. 

50                Da Zhang John Rong, Robert Chu, Wei R. Chen, and Hong Liu, “DQE Measurements in Magnification X-ray Imaging”, Journal of X-Ray Science and Technology, 14, 141-150, 2006.

51                Jared J. Crochet, Surya C Gnyawali, Yichao Chen, Evan C. Lemley, Lihong V. Wang and Wei R. Chen, “Temperature Distribution in Selective Laser-Tissue Interaction”, Journal of Biomedical Optics, Vol. 11, 034031, 1-10, 2006.

52                Wei R. Chen and Zheng Huang, “Biophotonics and Immune Responses – Highlights from a new SPIE Photonics West Conference (BIOS 2006)”, Photodiagnosis and Photodynamic Therapy, Vol. 3, 184-189, 2006.

53                Wei R. Chen, Kenneth E. Bartels, Hong Liu, and Robert E. Nordquist, “Laser-Photothermal Effect on Skin Tissue – Damage and Recovery”, Journal of X-Ray Science and Technology, 14, 207-215, 2006.

54                  Mark F. Naylor, Wei R. Chen, T. Kent Teague, Lisa Perry, and Robert E. Nordquist, “In Situ Photo Immunotherapy: A Tumor-Directed Treatment Modality for Melanoma”, British Journal of Dermatology, 155, 1287-1292, 2006.

55                Xingwei Wang, Shibo Li, Hong Liu, John J. Mulvihill, Wei R. Chen, and Bin Zheng, “A Computer-Aided Method to Expedite the Evaluation of Prognosis for Childhood Acute Lymphoblastic Leukemia”, Technology in Cancer Research and Treatment 5(4), 429-436, 2006.

56                Da Zhang, John Rong, Wei R. Chen, Xizhen Wu and Hong Liu, “Impact of Additive Noise on System Performance of a Digital X-ray Imaging System”, IEEE Transactions on Biomedical Engineering, 54, 69-73, 2007.

57                Yinyuan Wu, Da Xing, Lei Liu, Tongsheng Chen, and Wei R. Chen, “Fluorescence Resonance Energy Transfer Analysis of Bid Activation in Living Cells during Ultraviolet-induced Apoptosis”, Acta Biochimica et Biophysica Sinica, 39 (1), 37–45, 2007.

58                Feng Wu, Lan Zhou, and Wei R. Chen, “Host antitumour immune responses to HIFU ablation”, International Journal of Hyperthermia, 23(2): 165–171, 2007.

59                Liangzhong Xiang, Da Xing, Huaimin Gu, Diwu Yang, Sihua Yang, Lvming Zeng, and Wei R. Chen, “Real-time optoacoustic monitoring of vascular damage during photodynamic therapy treatment of tumor”, Journal of Biomedical Optics, Vol 12, 014001 (Feb) 2007.

60                Feng Wu, Gail ter Haar, and Wei R. Chen,High-intensity focused ultrasound ablation of breast cancer”, Expert Review of Anticancer Therapy, Vol 7, No. 6, 823-831, 2007.

61                Tongsheng Chen, Jinjun Wang, Da Xing, and Wei R. Chen, “Spatio-Temporal Dynamic Analysis of Bid Activation and Apoptosis Induced by Alkaline Condition in Human Lung Adenocarcinoma Cell”, Cellular Physiology and Biochemistry, Vol. 20, 569-578, (DOI:10.1159/000107540), 2007.

62                Shengnan Wu, Da Xing, Fang Wang, Tongsheng Chen, and Wei R. Chen, “Mechanistic Study of Apoptosis Induced by High Fluence Low Power Laser Irradiation Using Fluorescence Imaging Techniques”, Journal of Biomedical Optics, Vol. 12, 064015 (1-10), 2007.

63                Sihua Yang, Da Xing, Yeqi Lao, Diwu Yang, Lvming Zeng, Liangzhong Xiang, and Wei R. Chen, “Noninvasive monitoring of traumatic brain injury and post-traumatic rehabilitation with laser-induced photoacoustic imaging”, Applied Physics Letters, 90, 243902 (1-3), 2007.

64                Yinyuan Wu, Da Xing, Wei R. Chen, and Xichao Wang, “Bid is not required for Bax translocation during UV-induced apoptosis”, Cellular Signalling, Vol. 19 (12) 2468-2478, 2007.

65                Surya C. Gnyawali, Yichao Chen, Feng Wu, Kenneth E. Bartels, James P. Wicksted, Hong Liu, and Wei R. Chen, “Temperature Measurement on Tissue Surface during Laser Irradiation”, Medical and Biological Engineering and Computing, Vol. 46, 159-168, 2008.

PAPERS IN PRESS:

1.                  Abby Deans, Linda Hess, Michael Koss, Hong Liu, and Wei R. Chen, “Laser Photothermal Effects on Tumor Vasculature Using Laser Doppler Flowmetry”, Journal of X-Ray Science and Technology, 2008 (in press).

2.                  Lei Liu, Da Xing, Wei R. Chen, Tongsheng Chen, Yihui Pei, and Xuejuan Gao,“Calpain-mediated pathway dominates cisplatin-induced apoptosis in human lung adenocarcinoma cells as determined by real-time single cell analysis”, International Journal of Cancer, 2008 (in press).

3.                  Yichao Chen, Surya C. Gnyawali, Feng Wu, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “Three-dimensional mapping of temperature distribution in biological tissues using MRI during laser phototherapy”, Journal of Biomedical Optics, 2008 (in press).

4.                  Feifan Zhou, Da Xing, and Wei R. Chen, “Dynamics and mechanism of HSP70 translocation induced by photodynamic therapy treatment”, Submitted to Cancer Letters, 2008 (in press).

5.                  Feifan Zhou, Da Xing, Wei R. Chen, Shengnan Wu, and Lei Liu, “Intravital imaging of tumor apoptosis with FRET probes during tumor therapy”, Submitted to Journal of Biomedical Optics, 2008 (in press).

6.                  Yabing Tang, Da Xing*, Debin Zhu, and Wei R. Chen, “ PCR-free quantitative detection of genetically modified organism from raw materials – A novel electrochemiluminescence-based bio-barcode method, Submitted to Analytical Chemistry, 2008 (in press).

7.                  Xingwei Wang, Shibo Li, Hong Liu, Marc Wood, Wei R. Chen, and Bin Zheng, “Automated identification of analyzable metaphase chromosomes depicted on microscopic digital images“, Journal of Biomedical Informatics, 2008 (in press).

 

C.          BOOK CHAPTERS

1.         Zheng Huang, Hong Liu, and Wei R. Chen, Mechanisms and Applications of Photodynamic Therapy, in Fundamentals and Applications of Biophotonics in Dentistry, Editors Anil Kishen and Anand Asundi, (Imperial College Press, 2007), pp 154-181.

 D.          Proceeding Papers

1.                  Wei R. Chen and Rudolph C. Hwa, "Cross sections and multiplicity distributions with minijets", in Proc. of Shandong Workshop on Multiparticle Production, Jinan, China, 1987, edited by R. C. Hwa and Q.-B. Xie (World Scientific, Singapore, 1988), 276-282.

2.                  Wei R. Chen, "Massive cluster decay in multiparticle production", Conference of Particle and Fields, Bulletin of the American Physical Society, Jan. 1990.

3.                  Wei R. Chen and V. V. Dixit, "Debye-Huckel screening and the dissolution of the bound states", in Proc. of the 7th Winter Workshop on Nuclear Dynamics, Key West, Florida, 1991, edited by W. Bauer and J. Kapusta (World Scientific, Singapore, 1991) 238-241.

4.                  Wei R. Chen, Andrew Holt and Robert E. Nordquist, "Ablation of skin tissue by holmium YAG laser", SPIE Vol. 2134A, 342-351, 1994.

5.                  Wei R. Chen, Raleigh A. Holt and Robert E. Nordquist, "Laser hard tissue interaction: Energy transmission through human dental tissue using a holmium YAG laser", SPIE Vol. 2394, 68-77, 1995.

6.                  Wei R. Chen, Claudia L. Phillips, Kenneth E. Bartels, Robert L. Adams, and Robert E. Nordquist, "Indocyanine green in situ administration and photothermal destruction of tumor tissue using an 808 nm diode laser", SPIE Vol. 2681, 94-101, 1996.

7.                  Wei R. Chen, Baha Jassemnejad, Jason Crull, Edward Knobee, and Robert E. Nordquist, "Detection and characterization of chemical-induced abnormal tissue and rat tumor at different stages using fluorescence spectroscopy", SPIE Vol. 2679, 55-64, 1996.

8.                  Wei R. Chen, Kelly G. Wichert, Aaron K. Higgins, Kenneth E. Bartels, Robert L. Adams, and Robert E. Nordquist, "Effects of indocyanine green in treatment of murine mammary tumor by an 808 nm diode laser: an in vivo study", SPIE Vol. 2675, 114-121, 1996.

9.                  Wei R. Chen, David A. Okrongly, Robert L. Adams, and Robert E. Nordquist, “Laser-tissue photobiological interaction: a new mechanism for laser-sensitizer-immunoadjuvant treatment of metastatic cancers”, SPIE Vol. 2975, 290-297, 1997.

10.              Li-hong Wang, Wei R. Chen and Robert E. Nordquist, “Theoretical studies of optimal light delivery for tumor treatment”, SPIE Vol. 2975, 84-95, 1997.

11.              Wei R. Chen, Karen Robinson, Robert L. Adams, Anil Singhal and Robert E. Nordquist, “Anti-tumor immune responses induced by the treatment of photodynamic immunotherapy”, SPIE Vol. 3254, 27-34, 1998.

12.              Robert E. Nordquist, John A. Nordquist, James C. Agee, Chad M. Blomquist and Wei R. Chen, “Morphological studies of metastatic mammary rat tumors after laser immunotherapy treatment”, SPIE Vol. 3254, 36-41, 1998.

13.              Li-hong Wang, Guillermo Marquez, Robert E. Nordquist and Wei R. Chen, “Propagation and absorption of near-infrared laser light in photosensitizer-enhanced biological tissues”, SPIE Vol. 3254, 332-339, 1998.

14.              J. Paul Wood, Kenneth E. Bartels, Ellen B. Davidson, Jerry Ritchey, Terry W. Lehenbauer, Robert E. Nordquist, and Wei R. Chen, “Laser-immunotherapy of canine and feline neoplasia”, SPIE 3245, 432-440 1998.

15.              Wei R. Chen and Robert E. Nordquist, “Control of metastatic mammary tumor by laser immunotherapy through local treatment”, SPIE 3548, 75-82, 1998.

16.              Wei R. Chen, Ahmad El-Samad and Robert E. Nordquist, “Photothermal and immunological reactions against metastatic tumors using laser-photosensitizer-immunoadjuvant”, SPIE 3601, 75-81, 1999.

17.              Hangyi Jiang, Hong Liu, Wei R. Chen and L Laurie L. Fajardo, "Positional accuracy and sensitivity in X-ray Stereo-image guidance", SPIE Proceedings, 3595, 178-185, 1999.

18.              Hangyi Jiang, Hong Liu, and Wei R. Chen, "A calibration Technique for Monoplane Stereo X-ray systems in image guidance", SPIE Proceedings, Vol. 3911, 122-129, 2000.

19.              (Invited Paper) Wei R. Chen, Hong Liu, Anil K. Singhal, and Robert E. Nordquist, “Passive adoptive transfer of antitumor immunity induced by laser-dye-immunoadjuvant treatment in a rat metastatic breast cancer model”, SPIE Proceedings, Vol. 3914, 26-32, 2000.

20.              Andrea K. Ives, Wei R. Chen, Baha Jassemnejad, Kenneth E. Bartels, Hong Liu, John A. Nordquist and Robert E. Nordquist, “Laser-tissue photothermal interaction and tissue temperature change”, SPIE Proceedings, Vol. 3914, 94-101, 2000.

21.              Wei R. Chen, Hong Liu, Ken E. Bartels and Robert E. Nordquist, “Functions of laser light, laser-absorbing dye and immunoadjuvants in Photo Dynamic Immuno Therapy”, SPIE Proceedings, Vol. 4224, 322-330, 2000.

22.              Michael D. Lucroy, Wei R. Chen, Diana Sensney-Sears, Russell G. Higbee, and Kenneth E. Bartels, “Developing a subcutaneous murine breast cancer model for the evaluation of laser-induced hyperthermia”, Proceedings of the Veterinary Cancer Society 20th Annual Conference, October 15-18, 2000, Monterey, CA, p 87.

23.              Wei R. Chen, “Optimizing laser immunotherapy of tumors”, Bulletin of TherapeuticAdvances, LeadDiscovery, http://www.leaddiscovery.fsnet.co.uk/target-discovery/abstracts/0436.html.

24.              (Invited Paper) Wei R. Chen, Michael D. Lucroy, Hong Liu, Kenneth E. Bartels, Baha Jassemnejad, Shawn L. Barker, Punit Gandhi, and Robert E. Nordquist, “Immunoadjuvants in treatment of metastatic breast tumors using selective laser photothermal interaction”, SPIE Proceedings, Vol. 4257, 1-8, 2001.

25.              Michael D. Lucroy, Wei R. Chen, Diana Sensney-Sears, Russell G. Higbee, and Kenneth E. Bartels, “Improved light delivery for chromophore-enhanced laser-induced hyperthermia in a subcutaneous murine breast cancer model”, SPIE Proceedings, Vol. 4244, 561-566, 2001.

26.              Wei R. Chen, Hong Liu, and Robert E. Nordquist, “Mechanism of laser immunotherapy – role of immunoadjuvant and induction of anti-tumor immunity”, SPIE Proceedings, Vol. 4536, 82-89, 2002.

27.              Wei R. Chen, Hong Liu, and Robert E. Nordquist, “Monitoring of laser treatment of rat tumors using digital x-ray imaging technique”, SPIE Proceedings, Vol. 4615, 117-126, 2002.

28.              Fabrice Qunjj, Eric Potter, Wei R. Chen, and Hong Liu, “Impact of focal spot size on the spatial resolution of a digital x-ray imaging system for small animal studies”, SPIE Proceedings, Vol., 4615, 109-116, 2002.

29.              Hangyi Jiang, Wei R. Chen, and Hong Liu, “Effect of window function on noise power spectrum measurements in digital x-ray imaging”, SPIE Proceedings, Vol., 4615, 91-97, 2002.

30.              David Tang, Yuhua Li, Wei R. Chen, and Hong Liu, “Feasibility studies of high spatial resolution cardiac optical mapping system”, SPIE Proceedings, Vol., 4615, 127-136, 2002.

31.              (Invited Paper) Wei R. Chen, Hong Liu, Roman Wolf, Michael D. Lucroy, and Robert E. Nordquist “Function of immunoadjuvants in laser immunotherapy for treatment of metastatic breast tumors in rats”, SPIE Proceedings, Vol., 4617, 11-17, 2002.

32.              (Invited Paper) Thomas M. Cowan, Guangyu Liu, Sarah Simmons, Jeremy Real, Michael D. Lucroy, Kenneth E. Bartels, Robert E. Nordquist, and Wei R. Chen, “Selective photothermal interaction using near-infrared laser and laser-absorbing dye in gel phantom and chicken breast tissue”, SPIE Proceedings, Vol., 4617, 18-25, 2002.

33.              (Invited Paper) Wei R. Chen, Jerry W. Ritchey, Kenneth E. Bartles, Michael D. Lucroy, Hong Liu, and Robert E. Nordquist, “Laser immunotherapy in treatment of metastatic prostate tumors in rats”, SPIE Proceedings, Vol., 4707, 165-172, 2002.

34.              Christopher A. Bailey, Evan C. Lemley, and Wei R. Chen, “Theoretical Study of Selective Photo-Thermal Interactions Using Monte Carlo Simulations”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

35.              Sang Won Jeong, Fakhrildeen Albahadily, and Wei R. Chen, “Measurement of Optical Properties of Laser-Absorbing Dye Enhanced Gel Phantom for Selective Photothermal Interaction”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

36.              HemanthKumar Athiraman and Wei R. Chen, “Near-Infrared Laser and Laser-Absorbing Dye in Tissue Welding”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

37.              Jeremy W. Real and Wei R. Chen, “Optimization of selective energy absorption in tissue-simulating gelatin phantoms and chicken breast tissue”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

38.              (Invited Paper) Wei R. Chen, Hong Liu, Roman Wolf, Michael D. Lucroy, and Robert E. Nordquist, “Selective photothermal laser-tissue interaction with augmentation of immunoadjuvants in treatment of DMBA-4 metastatic mammary tumors in rats”, SPIE Proceedings, Vol. 4916, 37-42, 2002.

39.              (Invited Paper) Wei R. Chen, Hong Liu, Michael D. Lucroy and Robert E. Nordquist, “Anti-tumor immunity induced by local photothermal-immunoadjuvant therapy in a poorly immunogenic metastatic tumor model”, SPIE Proceedings 4961, 18-23, 2003.

40.              Thomas M. Cowan, Christopher A. Bailey, Hong Liu, and Wei R. Chen, “Optimization of operating parameters for selective photothermal interactions using 805-nm diode laser and indocyanine green”, SPIE Proceedings, Vol. 4961, 24-31, 2003.

41.              David Y. Tang, Yuhua Li, Jianan Y. Qu, Sunny S. Po, Eugene S. Patterson, Wei R. Chen, Warren M. Jackman, and Hong Liu, “Preliminary study of a dual CCD based ratiometric optical mapping system”, SPIE Proceedings, Vol. 4958, 273-278, 2003.

42.              (Invited Paper) Wei R. Chen, Kenneth E. Bartels, Jinghai Sun, Hong Liu, Robert E. Nordquist and Mladen Korbelik, “Dye-enhanced selective photothermal laser-tissue interaction and photodynamic therapy in combination with immunoadjuvant for cancer treatment”, SPIE Proceedings, Vol. 5254, 52-60, 2003.

43.              (Invited Paper) Sang won Jeong, Hong Liu, and Wei R. Chen, “Temperature control in deep tumor treatment”, SPIE Proceedings, Vol. 5068, 210-216, 2003.

44.              Qirong Zhang, Yuhua Li, Ben Steele, Wei R. Chen, Xizeng Wu, John Cheung,
Hong Liu,  "Contrast-detail analysis of a CMOS-based digital x-ray imaging
system", The Proceedings of the ISCA 19th International Conference on
Computers Applications (CATA-2004, ISBN: 1-880843-50-1), 51-54, 2004.

45.              Qiong Wang, Xizeng Wu, Wei R. Chen, John Cheung, and Hong. Liu, “Quantum efficiency of a digital x-ray imaging system for small animal studies, SPIE Proceedings Vol. 5318, 94-98, 2004.

46.              (Invited Paper) Wei R. Chen, Mladen Korbelik, Jinghai Sun, Hong Liu, and Robert E. Nordquist, “Enhancement of glycated chitosan in laser cancer treatment”, SPIE Proceedings, Vol. 5319, 80-86, 2004.

47.              Vinson G. Liu, Chris A. Bailey, Jared Crochet, and Wei R. Chen, “Simulation of selective photothermal interaction with dye enhancement”, SPIE Proceedings, Vol. 5319, 101-107, 2004.

48.              (Invited Plenary Paper) Wei R. Chen, Mladen Korbelik, Kenneth E. Bartels, Hong Liu, and Robert E. Nordquist, “Laser Immunotherapy: A Novel Approach for Metastatic Tumors”, SPIE Proceedings, Vol. 5474, 25-32, 2004.

49.              (Invited Paper) Wei R. Chen, Mladen Korbelik, Liu Hong, and Robert E. Nordquist, “Cancer Treatment by photothermal, photochemical and photobiological interactions”, SPIE Proceedings, Vol 5630, 1-7, 2005.

50.              Eric Potter, Fabrice Ouandji, Yuhua Li, Pascal Laignier, Preeti Kshirsagar, Wei R. Chen and Hong Liu, “An Observer-Based Study of an X-Ray Imaging System for Small Animal Research”, SPIE Proceedings, Vol 5692, 44-50, 2005.

51.              (Invited Paper) Wei R. Chen, Kenneth E. Bartels, Mladen Korbelik, Hong Liu, and Robert E. Nordquist, Synergistic effects of laser and adjuvant therapies for cancer – Progress in the development of novel cancer treatment methods using combinations of photothermal, photochemical, immunotherapy and chemotherapy”, SPIE Proceedings, Vol 5695, 1-6, 2005.

52.              Wei R. Chen, Kirill Andrienko, Kenneth E. Bartels, Steven D. Martin, Hong Liu, and Robert E. Nordquist, “Laser photothermal therapy in treatment of mouse melanoma”, SPIE Proceedings Vol 5695, 236-242, 2005.

53.              (Plenary Paper) Wei R. Chen, Kenneth E. Bartels, Hong Liu and Robert E. Nordquist, “Induction and detection of immune responses by photoimmunotherapy”, SPIE Proceedings, Vol. 5771, 1-7, 2005.

54.              Wei R. Chen, “Introduction”, SPIE Proceedings, Vol. 6087, xi-xiii, 2006.

55.              (Invited Paper) Zheng Huang, Hong Liu, and Wei R. Chen, “Light and Immune Systems – Activation of Immunological Activities”, SPIE Proceedings, Vol. 6087, 608701-1 – 608701-9, 2006.

56.              Mark F. Naylor Robert E. Nordquist, T. Kent Teague, Lisa A. Perry, and Wei R. Chen, “In Situ Photoimmunotherapy for Melanoma: Preliminary Clinical Result”, SPIE Proceedings, Vol. 6087, 608709-1 – 608709-7, 2006.

57.              Yichao Chen, Surya Gnyawali, Jeremy Bjorlie, Kirill Andrienko, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “Tissue temperature distribution measurement and laser immunotherapy for cancer treatment”, SPIE Proceedings, Vol. 6087, 60870H-1 – 60870H-11, 2006.

58.              Wei R. Chen, Zheng Huang, Kirill Andrienko, Stefan Stefanov, Roman F. Wolf and Hong Liu, “Effects of surgery, immunization, and laser immunotherapy on a non-immunogenic metastatic tumor model”, SPIE Proceedings, Vol 6163, 61630E-1–61630E-6, 2006.

59.              Yi Yang Zhou, Hans K. Pew, John Rong, Wei R. Chen, Laurie Fajardo, Xizeng Wu, and Hong Liu, "Phantom imaging with a prototype phase contrast radiography system", SPIE Proceedings, Vol 6163, 61630E-1– 61630E-7, 2006.

60.              Abby Deans, Linda Hess, Michael Koss, Hong Liu, and Wei R. Chen, “Monitoring perfusion changes in laser-treated tumors using laser Doppler flowmetry”,- SPIE Proceedings Vol 6084, 60840F1-60840F-8, 2006.

61.              Molly Donovan, Da Zhang, Wei R. Chen, and Hong Liu, “The characterization of a phase contrast x-ray imaging prototype”, SPIE Proceedings, Vol. 6436, 643608(1-9), 2007.

62.              Liangzhong Xiang, Da Xing, Huaimin Gu, Diwu Yang, Sihua Yang, Lvming Zeng, and Wei R. Chen, “Pulse laser integrated photodynamic therapy and photoacoustic imaging”, SPIE Proceedings, Vol. 64372B, 64372B(1-8), 2007.

63.              Mark F. Naylor, Robert E. Nordquist, T. Kent Teague, Lisa A. Perry, and Wei R. Chen, “In Situ Photoimmunotherapy for Melanoma: An Ongoing Phase I Clinical Trial”, SPIE Proceedings, Vol. 6438, 643807(1-9), 2007.

64.              Wei R. Chen, Abdiwahab Mohamed, Mark, F. Naylor, Kenneth E. Bartels, Jerry W. Ritchey, Hong Liu, and Robert E. Nordquist, “Cellular immunological effects of laser irradiation and immunoadjuvant application”, SPIE Proceedings, Vol. 6438, 64380B(1-11), 2007.

65.              Yichao Chen, Surya C. Gnyawali, Feng Wu, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “Tissue temperature distribution measurement by MRI and laser immunology for cancer treatment”, SPIE Proceedings, Vol. 6438, 64380C(1-12), 2007.

66.              Surya C. Gnyawali, Yichao Chen, Feng Wu, Kenneth E. Bartels, Jerry W. Ritchey, James P. Wicksted, Hong Liu, and Wei R. Chen, “Determination of Surface Temperature Distribution in Biological Tissues during Laser-Immunotherapy”, SPIE Proceedings, Vol. 6438, 64380D(1-11), 2007.

67.              Lei Liu, Da Xing, Yihui Pei, and Wei R. Chen, “Real-time single cell analysis of Bid cleavage and translocation in cisplatin-induced apoptosis”, SPIE Proceedings, Vol. 6438, 64380G(1-9), 2007.

68.              Yichao Chen, Surya C. Gnyawali, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “MRI 3D tissue temperature distribution measurement”, SPIE Proceedings, Vol. 6438, 64380N(1-8), 2007.

69.         Lei Liu, Da Xing, and Wei R. Chen, “Sub-cell FRET imaging for determination of signaling pathway of cell apoptosis during tumor therapy”, SPIE Proceedings, Vol. 6534 653402-(1-10), 2007.

70.       Feifan Zhou, Da Xing, Wei R. Chen, “The single cell analysis of HSP70 expression on tumor cell surface induced by PDT in living cells”, SPIE Proceedings, Vol. 6534 65341G-(1-8), 2007.

Some related papers:

Can Res 2001 paper.pdf

Can Res 2002 paper.pdf

1999 Int J Can Paper

1999 Int J Can immunochemical study.pdf

 

 

Dr. Wei R. Chen
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Last updated: March 04, 2008.