Research

 

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Laser Immunotherapy
Laser-tissue Interactions
Monte Carlo Simulation
X-Ray Imaging
Chemotherapy
Laser Tissue Welding
MRI guided treatment

 

 

Research Projects Currently in Progress

Laser Immunotherapy Treatment of Metastatic Tumors:     Combining selective laser-photothermal interaction and a novel cancer treatment immunoadjuvant, together with several collaborators, we have developed a cancer treatment modality for metastatic tumors.

 

 Monte Carlo Simulation of Selective Photothermal Effects:    Computer simulations have been conducted to determine the parameters of laser and laser-absorbing dye in order to achieve optimal selective photothermal destruction of target tumors using laser irradiation while sparing the normal surrounding tissue. We are trying to develop a photothermal treatment protocol for cancer treatment.

 

Laser-Tissue Photothermal Interactions:    Experiments are being carried out to determine the temperature increase in both tissue and gel phantom due to laser irradiation with and without the absorption enhancement of dye. This research will provide information for laser cancer treatment.

 

Laser-Tissue Welding:    Using a laser and laser absorbing dye, we are currently conducting experiments on laser tissue welding. The objective of this research is to explore the clinical applications of laser use in wound closure without conventional suturing and with  low probability for infection.   

 

MRI Guided Laser Cancer Treatment:    We are currently collaborating with researchers at the Oklahoma Medical Research Foundation to develop an imaging guided laser treatment modality for cancers. The Magnetic Resonance Imaging will be used to detect the tumor and to monitor the tissue temperature distribution during treatment. This project, funded by a NIH grant will enhance and extend the current laser immunotherapy research.

 

Other Research Projects

X-Ray Imaging for Disease Detection and Treatment:    In collaboration with a research group from the University of Oklahoma, we have been conducting research using x-ray techniques in disease diagnostics and treatment. Specifically, we are trying to develop a method and technique for an x-ray guided laser treatment modality for cancers.

 

Research on Methods of Chemotherapy Cancer Treatment:    We have been working on novel approaches in cancer treatment using scheduled combinations of different chemotherapy drugs in cancer treatment, in collaboration with researchers and oncologists in the Oklahoma City metro area. Both laboratory experiments and clinical trials have been conducted to search for the optimal chemotherapy drugs and procedures.

 

 

 

Dr. Wei R. Chen
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Last updated: August 26, 2004.